BioCule - The Second Dimension in Genetics

BioCule

About

BioCule is revolutionizing the way complex nucleic acid samples are analysed.

 

Contacts

Email: biocule at biocule.com

phone: +354-699 3309

 

Links

www.pubmed.com

www.ncbi.nih.gov

About the website

We are now on Facebook.

www.facebook.com/BioCule

 

Comments about the website should be sent to the email above.

BioCule produces and sells instruments and single use gel cards for Two-Dimensional Electrophoresis of nucleic acids.

 

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BioCule's Two-Dimensional Electrophoresis of nucleic acids can be used for:

Sample preparation for microarray analysis

Normalisation of nucleic acid samples

Library preparation for next-generation sequencing

Synthesis and handling of genomic and transcriptomic libraries

Genomic scale amplification

Detection of DNA damage either in vivo or in biobank samples.

News

 

2011 May

BioCule introduces a novel single-use microgel card that can be used with the μ4-2D instrument to perform Two-Dimensional electrophoresis in less than 20 min.  The instrument and the gelcard was developed in cooperation with Wideblue www.wide-blue.com. 

 

 

 

 

 

 

 

 

 

 

 

 

 

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2011 May

BioCule introduced its results on European Society of Human Genetics conference in Amsterdam.

A) The power of using 2D-SDE and 2D-CDE to detect crosslinks in genomic DNA

B) The power of using 2D-SDE to optimize cDNA synthesis prior to microarray analysis

 

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2011 May

BioCule 's results presented gets selected as 1 out of 12 of approx. 1200 posters to give an oral presentation at the Berlin2011 conference.

 

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2011 May

BioCule introduced results on the  IFCC WorldLab Berlin 2011 Conference.   Those results from microarray experiments clearly demonstrates the power of using Two-Dimensional Strandness-dependent electrophoresis to validate complex nucleic acid sample quality prior to labeling and hybridization.

www.berlin2011.org

 

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2011

BioCule introduces results from microarray experiments that clearly demonstrates the power of using Two-Dimensional Strandness-dependent electrophoresis to validate complex nucleic acid sample quality prior to labeling and hybridization.

 

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2010

BioCule initate research to optimize normalization of complex nucleic acid samples for High Throughput Sequencing

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 2009

BioCule attends Young Company Finance conference in Scotland

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 ‎2008
BioCule starts development of prototypes of 2D electrophoresis instrument and consumables.

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January 2007.

BioCule publish 2D-SDE patented protocol in one of Nature magazines.

An article describing in details the 2D-SDE protocol for analyzing complex nucleic acid samples was published online in Nature Protocols January 25th.

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December 2006. Genetic engineering news interview.

GEN's Editor-in-Chief John Sterling talks with Jon J. Jonsson, M.D., Ph.D., from the University of Iceland and chairman of the board of BioCule about 2D Elctrophoresis of nucleic acids for biomarker discovery, quality, and vaildation.

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September 2006.

 BioCule participates in Discovery-2-Diagnostics Conference and Exhibition in Boston.

Members of BioCule participated in Discovery-2-Diagnostics conference and exhibition in Boston.

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April 2006.

Prototype of the μ4™ electrophoresis system completed.

Scientists at BioCule have completed the prototype of a micogel electrophoresis instrument called μ4™. The μ4™ instrument completes two-dimensional electrophoresis in 10 minutes, allowing separation between single-stranded and double-stranded DNA fractions in complex samples. Furthermore, the instrument can conveniently be used to analyse DNA in only 4 minutes, using one dimension electrophoresis.

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March 2006. Article describing 2D-SDE published in Analytical Biochemistry.

An article describing BioCule's 2D-SDE method has been published in Analytical Biochemistry. 2D-SDE is a patent pending method.

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February 2005. BioCule signs consultancy contract with BioKapital Ltd.

BioCule and BioKapital have signed a contract regarding further business development of BioCule. BioKapital is a consultancy dedicated to assisting Scandinavian and British organisations in the biotechnology, healthcare, information technology and life sciences industries with fundraising and to develop their businesses, products and technologies.

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September 2004. BioCule invited to participate in The Nordic Venture summit.

The Nordic Venture Summit took place in Copenhagen 27th of September 2004. The event offers entrepreneurs and key investors, advisors and corporate partners a meeting place in an exclusive setting. Gudmundur Gunnarsson CEO, presented the company.

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Mai 2004. BioCule completes next Financing Round.

BioCule has now completed a round of start-up phase financing. Two investors bought shares in the company.

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February 2004. Article describing BioCule's 2D-CDE method published in Nucleic Acid Research.

BioCule has now published an article describing method to facilitate work with complex genomic samples. 2D-CDE is a patent pending method that can be used for: (i) separation of mismatched or unmatched DNA fragments from those perfectly matched; (ii) simultaneous, diagnostic, mismatch scanning of multiple fragments; (iii) isolation of damaged DNA fragments from undamaged fragments; and (iv) estimation of reannealing efficiency of complex DNA samples.

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